{"id":2309,"date":"2018-03-27T09:52:36","date_gmt":"2018-03-27T00:52:36","guid":{"rendered":"https:\/\/mbm.me.es.osaka-u.ac.jp\/?p=2309"},"modified":"2020-03-23T19:09:27","modified_gmt":"2020-03-23T10:09:27","slug":"%e8%ab%96%e6%96%87%e3%82%a2%e3%82%af%e3%82%bb%e3%83%97%e3%83%88-fujiwara-et-al-plos-one","status":"publish","type":"post","link":"https:\/\/mbm.me.es.osaka-u.ac.jp\/?p=2309","title":{"rendered":"\u8ad6\u6587\u30a2\u30af\u30bb\u30d7\u30c8 Fujiwara et al., PLOS ONE"},"content":{"rendered":"<p>\u30dd\u30b9\u30c9\u30af\u306e\u85e4\u539f\u3067\u3059\u3002\u3053\u3053\u6570\u65e5\u306e\u6696\u304b\u3055\u3067\u3001\u8c4a\u4e2d\u30ad\u30e3\u30f3\u30d1\u30b9\u306e\u685c\u3082\u4e00\u6c17\u306b\u958b\u304d\u59cb\u3081\u307e\u3057\u305f\u3002\u3082\u3046\u6625\u3067\u3059\u306d\u3002<\/p>\n<p>\u3055\u3066\u3001PLOS ONE\u306b\u6295\u7a3f\u3057\u305f\u8ad6\u6587\u304c\u5148\u90313\u670820\u65e5\u306b\u30a2\u30af\u30bb\u30d7\u30c8\u3055\u308c\u307e\u3057\u305f\uff01<\/p>\n<p>Fujiwara et al., PLOS ONE, in press.<br \/>\n\u201cSolo, a RhoA-targeting guanine nucleotide exchange factor, is critical for hemidesmosome formation and acinar development in epithelial cells\u201d<\/p>\n<p>\u4eca\u56de\u306e\u8ad6\u6587\u3067\u306f\u3001Rho\u30d5\u30a1\u30df\u30ea\u30fc\u6d3b\u6027\u5316\u56e0\u5b50\u306e\u4e00\u3064\u3067\u3042\u308bSolo\u306b\u7740\u76ee\u3057\u3001\u4e0a\u76ae\u7d30\u80de\u306e\u7d30\u80de-\u57fa\u8cea\u9593\u63a5\u7740\u3084\u5f62\u614b\u5f62\u6210\u306e\u5206\u5b50\u30e1\u30ab\u30cb\u30ba\u30e0\u3092\u89e3\u6790\u3057\u3066\u3044\u307e\u3059\u3002\u7d30\u80de-\u57fa\u8cea\u9593\u63a5\u7740\u306b\u767a\u751f\u3059\u308b\u529b\u306e\u53ef\u8996\u5316\u89e3\u6790\uff08\u51fa\u53e3\u7814\u306e\u72ec\u81ea\u6280\u8853\uff09\u306b\u52a0\u3048\u3001\u7d30\u80de\u751f\u7269\u5b66\u7684\u30fb\u751f\u5316\u5b66\u7684\u624b\u6cd5\u3092\u7d44\u307f\u5408\u308f\u305b\u3066\u5b9f\u9a13\u3092\u884c\u3044\u307e\u3057\u305f\u3002<\/p>\n<p>\u305d\u306e\u7d50\u679c\u3001Solo\u304c\u4e0a\u76ae\u7d30\u80de\u7279\u7570\u7684\u306a\u7d30\u80de-\u57fa\u8cea\u9593\u63a5\u7740\u3067\u3042\u308b\u201d\u30d8\u30df\u30c7\u30b9\u30e2\u30bd\u30fc\u30e0\u201d\u306e\u5f62\u6210\u304a\u3088\u3073\u4e09\u6b21\u5143\u74b0\u5883\u4e0b\u3067\u306e\u817a\u623f\u5f62\u6210\u306b\u5fc5\u8981\u3067\u3042\u308b\u3053\u3068\u304c\u5206\u304b\u308a\u307e\u3057\u305f\u3002\u3055\u3089\u306b\u3001\u7d30\u80de\u306e\u529b\u306e\u767a\u751f\u90e8\u4f4d\u3068Solo\u306e\u5c40\u5728\u306b\u76f8\u95a2\u304c\u3042\u308b\u3053\u3068\u3092\u660e\u3089\u304b\u306b\u3057\u307e\u3057\u305f\u3002\u672c\u7814\u7a76\u6210\u679c\u306f\u3001\u529b\u5b66\u7684\u74b0\u5883\u306b\u5fdc\u3058\u305f\u7d30\u80de\u5fdc\u7b54\u306e\u5206\u5b50\u30e1\u30ab\u30cb\u30ba\u30e0\u306e\u4e00\u7aef\u3092\u660e\u3089\u304b\u306b\u3059\u308b\u3082\u306e\u3068\u8003\u3048\u3066\u3044\u307e\u3059\u3002\u306a\u304a\u3001\u672c\u7814\u7a76\u306f\u6771\u5317\u5927\u5b66\u751f\u547d\u79d1\u5b66\u7814\u7a76\u79d1\u30fb\u6c34\u91ce\u7814\u7a76\u5ba4\u3067\u306e\u7814\u7a76\u6210\u679c\u3082\u542b\u3093\u3067\u304a\u308a\u307e\u3059\u3002<\/p>\n<p>\u203b\u73fe\u5728\u306f\u307e\u3060 in press\u3067\u3059\u304c\u3001Journal HP\u306b\u63b2\u8f09\u3055\u308c\u307e\u3057\u305f\u3089\u30ea\u30f3\u30af\u3092\u7814\u7a76\u696d\u7e3e\u306e\u30da\u30fc\u30b8\u306b\u63b2\u793a\u81f4\u3057\u307e\u3059<\/p>\n","protected":false},"excerpt":{"rendered":"<p>\u30dd\u30b9\u30c9\u30af\u306e\u85e4\u539f\u3067\u3059\u3002\u3053\u3053\u6570\u65e5\u306e\u6696\u304b\u3055\u3067\u3001\u8c4a\u4e2d\u30ad\u30e3\u30f3\u30d1\u30b9\u306e\u685c\u3082\u4e00\u6c17\u306b\u958b\u304d\u59cb\u3081\u307e\u3057\u305f\u3002\u3082\u3046\u6625\u3067\u3059\u306d\u3002 \u3055\u3066\u3001PLOS ONE\u306b\u6295\u7a3f\u3057\u305f\u8ad6\u6587\u304c\u5148\u90313\u670820\u65e5\u306b\u30a2\u30af\u30bb\u30d7\u30c8\u3055\u308c\u307e\u3057\u305f\uff01 Fujiwara et al., PLOS  [&hellip;]<\/p>\n","protected":false},"author":3,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[4],"tags":[11],"class_list":["post-2309","post","type-post","status-publish","format-standard","hentry","category-news","tag-11"],"_links":{"self":[{"href":"https:\/\/mbm.me.es.osaka-u.ac.jp\/index.php?rest_route=\/wp\/v2\/posts\/2309","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/mbm.me.es.osaka-u.ac.jp\/index.php?rest_route=\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/mbm.me.es.osaka-u.ac.jp\/index.php?rest_route=\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/mbm.me.es.osaka-u.ac.jp\/index.php?rest_route=\/wp\/v2\/users\/3"}],"replies":[{"embeddable":true,"href":"https:\/\/mbm.me.es.osaka-u.ac.jp\/index.php?rest_route=%2Fwp%2Fv2%2Fcomments&post=2309"}],"version-history":[{"count":0,"href":"https:\/\/mbm.me.es.osaka-u.ac.jp\/index.php?rest_route=\/wp\/v2\/posts\/2309\/revisions"}],"wp:attachment":[{"href":"https:\/\/mbm.me.es.osaka-u.ac.jp\/index.php?rest_route=%2Fwp%2Fv2%2Fmedia&parent=2309"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/mbm.me.es.osaka-u.ac.jp\/index.php?rest_route=%2Fwp%2Fv2%2Fcategories&post=2309"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/mbm.me.es.osaka-u.ac.jp\/index.php?rest_route=%2Fwp%2Fv2%2Ftags&post=2309"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}