(* Corresponding author)
Preprints
Ueda, Y., Deguchi, S.*, Adaptive flexibility of cytoskeletal structures through nonequilibrium entropy production. arXiv.
https://arxiv.org/abs/2411.14291
Ding, S., Chou, P.E., Deguchi, S.*, Kim, T.*, Impacts of structural properties of myosin II filaments on force generation. bioRxiv.
https://doi.org/10.1101/2024.11.12.623186
Ueda, Y., Deguchi, S.*, Intracellular order formation through stepwise phase transitions. arXiv.
https://arxiv.org/abs/2408.14242
Ueda, Y., Deguchi, S.*, Nonthermal driving forces in cells revealed by nonequilibrium fluctuations. arXiv.
https://arxiv.org/abs/2408.06683
Chantachotikul, P., Liu, S., Furukawa, K., Deguchi, S.*, AP2A1 is upregulated upon replicative senescence of human fibroblasts to strengthen focal adhesions via integrin β1 translocation along stress fibers. bioRxiv.
https://biorxiv.org/cgi/content/short/2023.08.19.553998v1
Saito, N., Matsui, T.S., Matsunaga, D., Furukawa, K., Deguchi, S.*, A model explaining environmental stiffness-dependent migration of fibroblasts with a focus on maturation of intracellular structures. bioRxiv.
https://doi.org/10.1101/2022.12.30.522353
Refereed Journals
2024
Deguchi, S.*, Kawashima, K., Noninvasive measurement of compliance and viscoelastic properties of the human airway. Journal of Biorheology (invited paper) accepted.
Li, H., Liu, S., Deguchi, S.*, Matsunaga, M.*, Diffusion model predicts the geometry of actin cytoskeleton from cell morphology. PLOS Computational Biology 20(8), e1012312.
https://journals.plos.org/ploscompbiol/article?id=10.1371/journal.pcbi.1012312
Ueda, Y., Matsunaga, D., Deguchi, S.*, Asymmetric response emerges between creation and disintegration of force-bearing subcellular structures as revealed by percolation analysis. Integrative Biology 16, zyae012.
https://doi.org/10.1093/intbio/zyae012
Buenaventura, A., Saito, T., Kanao, T., Matsunaga, D., Matsui, T.S., Deguchi, S.*, Intracellular macromolecular crowding within individual stress fibers analyzed by fluorescence correlation spectroscopy. Cellular and Molecular Bioengineering 17, 165-176.
https://doi.org/10.1007/s12195-024-00803-4
Ding, S., Deguchi, S., Kim, T.*, Unraveling a key molecular player governing pulmonary alveolar development. American Journal of Respiratory Cell and Molecular Biology 70(4), 237-238 (commentary).
https://doi.org/10.1165/rcmb.2024-0025ED
2023
Saito, T.*, Deguchi, S.*, Advancing FRAP for cell studies: Where there is a new method, there is a new field. Journal of Biomechanical Science and Engineering 18, 4, 23-00028 (review paper).
https://doi.org/10.1299/jbse.23-00028
Ueda, Y., Deguchi, S.*, Emergence of multiple set-points of cellular homeostatic tension. Journal of Biomechanics 151, 111543.
https://doi.org/10.1016/j.jbiomech.2023.111543
Saito, T.*, Deguchi, S.*, CM-FRAP – Continuum mechanics-based fluorescence recovery after photobleaching. Current Protocols 3, e655.
https://doi.org/10.1002/cpz1.655
Saito, T., Matsunaga, D., Deguchi, S.*, Long-term fluorescence recovery after photobleaching (FRAP). Methods in Molecular Biology 2600, 311-322.
https://doi.org/10.1007/978-1-0716-2851-5
2022
Saito, T., Matsunaga, D., Matsui, T.S., Deguchi, S.*, Long-term molecular turnover of actin stress fibers revealed by advection-reaction analysis in fluorescence recovery after photobleaching. PLoS ONE 17(11), e0276909.
https://doi.org/10.1371/journal.pone.0276909
Ueda, Y., Matsunaga, D., Deguchi, S.*, A statistical mechanics model for determining the length distribution of actin filaments under cellular tensional homeostasis. Scientific Reports 12, 14466, 2022.
https://doi.org/10.1038/s41598-022-18833-1
Saito, T.*, Matsunaga, D., Deguchi, S.*, Analysis of chemomechanical behavior of stress fibers by continuum mechanics-based FRAP. Biophysical Journal 121, 2921-2930, 2022. Selected as Cover.
https://doi.org/10.1016/j.bpj.2022.06.032
Hamaguchi, H., Dohi, K., Sakai, T., Taoka, M. Isobe, T., Matsui, T.S., Deguchi, S., Furuichi, Y., Fujii, N.L., Manabe, Y.*, PDGF-B secreted from skeletal muscle enhances myoblast proliferation and myotube maturation via activation of the PDGFR signaling cascade. Biochemical and Biophysical Research Communications 639, 169-175.
https://doi.org/10.1016/j.bbrc.2022.11.085
Hamaguchi, H., Matsui, T.S., Deguchi, S., Furuichi, Y., Fujii, N.L., Manabe, Y.*, Establishment of a system evaluating the contractile force of electrically stimulated myotubes from wrinkles formed on elastic substrate. Scientific Reports 12, 13818, 2022. EurekAlert ScienMag Mirage News Bioengineer.org news-medical.net
https://doi.org/10.1038/s41598-022-17548-7
Sugita, S.*, Hozaki, M., Matsui, T.S., Nagayama, K., Deguchi, S., Nakamura, M., Polarized light retardation analysis allows for the evaluation of tension in individual stress fibers. Biochemical and Biophysical Research Communications 620, 49-55, 2022.
https://doi.org/10.1016/j.bbrc.2022.06.066
Ueda, N., Maekawa, M., Matsui, T.S., Deguchi, S., Takata, T., Katahira, J., Higashiyama, S., Hieda, M.*, Inner nuclear membrane protein, SUN1, is required for cytoskeletal force generation and focal adhesion maturation. Frontiers in Cell and Developmental Biology 10, 885859, 2022.
https://doi.org/10.3389/fcell.2022.885859
Li, H.†, Matsunaga, D.†,*, Matsui, T.S., Aosaki, H., Kinoshita, Inoue, K., Doostmohammadi, A., Deguchi, S.*, Wrinkle force microscopy: a machine learning based approach to predict cell mechanics from images. Communications Biology 5, 361, 2022. († co-first author)
https://doi.org/10.1038/s42003-022-03288-x
Liu, S., Matsui, T.S., Kang, N., Deguchi, S.*, Analysis of senescence-responsive stress fiber proteome reveals reorganization of stress fibers mediated by elongation factor eEF2 in HFF-1 cells. Molecular Biology of the Cell 33, ar10, 1-11, 2022.
https://doi.org/10.1091/mbc.E21-05-0229
2021
Kang, N., Matsui, T.S., Liu, S., Deguchi, S.*, ARHGAP4-SEPT2-SEPT9 complex enables both up- and down-modulation of integrin-mediated focal adhesions, cell migration, and invasion. Molecular Biology of the Cell, available online.
https://doi.org/10.1091/mbc.E21-01-0010
Saito, T., Matsunaga, D., Matsui, T.S., Noi, K., Deguchi, S.*, Determining the domain-level reaction-diffusion properties of an actin-binding protein transgelin-2 within cells, Experimental Cell Research 404, 112619, 2021.
https://doi.org/10.1016/j.yexcr.2021.112619
Huang, W., Matsui, T.S., Saito, T., Kuragano, M., Takahashi, M., Kawahara, T., Sato, M., Deguchi, S.*, Mechanosensitive myosin II but not cofilin primarily contributes to cyclic cell stretch-induced selective disassembly of actin stress fibers, American Journal of Physiology Cell Physiology 320, C1153–C1163, 2021.
https://doi.org/10.1152/ajpcell.00225.2020
Kang, N., Matsui, T.S., Deguchi, S.*, Statistical profiling reveals correlations between the cell response to and structural sequence of Rho-GAPs, Cytoskeleton 78, 67-76, 2021.
https://doi.org/10.1002/cm.21659
Saito, T., Huang, W., Matsui, T.S., Kuragano, M., Takahashi, M., Deguchi, S.*, What factors determine the number of nonmuscle myosin II in the sarcomeric unit of stress fibers? Biomechanics and Modeling in Mechanobiology 20, 155-166, 2021.
https://doi.org/10.1007/s10237-020-01375-8
2020
Fujiwara, S.*, Deguchi, S., Magin, T.M.*, Disease-associated keratin mutations reduce traction forces and compromise adhesion and collective migration, Journal of Cell Science, 133(14), 2020.
https://doi.org/10.1242/jcs.243956
Li, H., Matsunaga, D.*, Matsui, T.S., Aosaki, H., Deguchi, S.*, Image based cellular contractile force evaluation with small-world network inspired CNN: SW-UNet, Biochemical and Biophysical Research Communications, 530(3), 527-532, 2020.
Video
https://doi.org/10.1016/j.bbrc.2020.04.134
Kang, N., Matsui, T.S., Liu, S., Fujiwara, S., Deguchi, S.*, Comprehensive analysis on the whole Rho-GAP family reveals that ARHGAP4 suppresses EMT in epithelial cells under negative regulation by Septin9, FASEB Journal, 34, 8326-8340, 2020.
https://doi.org/10.1096/fj.201902750RR
Okamoto, T., Matsui, T.S., Ohishi, T., Deguchi, S.*, Helical structure of actin stress fibers and its possible contribution to inducing their direction-selective disassembly upon cell shortening, Biomechanics and Modeling in Mechanobiology, 19, 543-555, 2020.
https://doi.org/10.1007/s10237-019-01228-z
Nehwa, F.J., Matsui, T.S., Li, H., Matsunaga, D., Deguchi, S.*, Multi-well plate cell contraction assay detects negatively correlated cellular responses to pharmacological inhibitors in contractility and migration, Biochemical and Biophysical Research Communications, 521(2), 527-532, 2020.
https://doi.org/10.1016/j.bbrc.2019.10.160
2019
Fujiwara, S.*, Matsui, T.S., Ohashi, K., Mizuno, K.*, Deguchi, S.*, Keratin-binding ability of the N-terminal Solo domain of Solo is critical for its function in cellular mechanotransduction, Genes to Cells, 24(5), 390-402, 2019.
https://doi.org/10.1111/gtc.12682
Matsui, T.S., Deguchi, S.*, Spatially selective MRLC regulation is absent in dedifferentiated vascular smooth muscle cells but is partially induced by fibronectin and Klf4, American Journal of Physiology Cell Physiology, 316(4), C509-521, 2019.
https://doi.org/10.1152/ajpcell.00251.2017
2018
Matsui, T.S., Ishikawa, A., Deguchi, S.*, Transgelin-1 (SM22α) interacts with actin stress fibers and podosomes in smooth muscle cells without using its actin binding site, Biochemical and Biophysical Research Communications, 505(3), 879-884, 2018.
https://doi.org/10.1016/j.bbrc.2018.09.176
Matsui, T.S., Wu, H., Deguchi, S.*, Deformable 96-well cell culture plate compatible with high-throughput screening platforms, PLOS ONE, 13(9), e0203448, 2018.
https://doi.org/10.1371/journal.pone.0203448
Fujiwara, S.*, Matsui, T.S., Ohashi, K., Deguchi, S.*, Mizuno, K.*, Solo, a RhoA-targeting guanine nucleotide exchange factor, is critical for hemidesmosome formation and acinar development in epithelial cells, PLOS ONE, 13(4), e0195124, 2018.
https://doi.org/10.1371/journal.pone.0195124
Hirose, K., Aoki, T., Furukawa, T., Fukushima, S., Niioka, H., Deguchi, S., Hashimoto, M.*, Coherent anti-Stokes Raman scattering rigid endoscope toward robot-assisted surgery, Biomedical Optics Express, 9(2), 387-396, 2018.
https://doi.org/10.1364/BOE.9.000387
2017
Ichikawa, T., Kita, M., Matsui, T.S., Ichikawa-Nagasato, A., Araki, T., Chiang, S.H., Sezaki, T., Kimura, Y., Ueda, K., Deguchi, S., Saltiel, A.R., Kioka, N.*, Vinexin family (SORBS) proteins play different roles in stiffness-sensing and contractile force generation, Journal of Cell Science, 130, 3517-3531, 2017.
https://doi.org/10.1242/jcs.200691
Fukuda, S.P., Matsui, T.S., Ichikawa, T., Furukawa, T., Kioka, N., Fukushima, S., Deguchi, S.*, Cellular force assay detects altered contractility caused by a nephritis-associated mutation in nonmuscle myosin IIA, Development, Growth & Differentiation, 59(5), 423-433, 2017.
http://doi.org/10.1111/dgd.12379
Deguchi S.*, Saito, A.C., Matsui, T.S., Huang, W.J., Sato, M., The opposite mechano-response of paxillin phosphorylation between subcellular and whole-cell levels is explained by a minimal model of cell–substrate adhesions, Journal of Biomechanical Science and Engineering, 12(2), 16-00670, 2017.
[JBSE Papers of the Year]
http://doi.org/10.1299/jbse.16-00670
Yokoyama, S., Matsui, T.S., Deguchi, S.*, Microcontact peeling: a cell micropatterning technique for circumventing direct adsorption of proteins to hydrophobic PDMS, Current Protocols in Cell Biology, 75, 10.21.1-10.21.8, 2017.
https://doi.org/10.1002/cpcb.22
Yokoyama, S., Matsui, T.S., Deguchi, S.*, New wrinkling substrate assay reveals traction force fields of leader and follower cells undergoing collective migration, Biochemical and Biophysical Research Communications, 482, 975-979, 2017.
[F1000Prime recommended by Faculty of 1000]
https://doi.org/10.1016/j.bbrc.2016.11.142
Ohishi, T., Noda, H., Matsui, T.S., Jile, H., Deguchi, S.*, Tensile strength of oxygen plasma-created surface layer of PDMS, Journal of Micromechanics and Microengineering, 27, 015015, 2017.
https://doi.org/10.1088/0960-1317/27/1/015015
2016
Deguchi, S.*, A possible common physical principle that underlies animal vocalization: theoretical considerations with an unsteady airflow-structure interaction model, Journal of Biomechanical Science and Engineering, 11(4), 16-00414, 2016.
[JBSE Papers of the Year]
[JSME Medal for Outstanding Paper]
https://doi.org/10.1299/jbse.16-00414
Sakane, Y., Yoshizawa, S., Nishimura, M., Tsuchiya, Y., Matsushita, N., Miyake, K., Horikawa, K., Imoto, I., Mizuguchi, C., Saito, H., Ueno, T., Matsushita, S., Haga, H., Deguchi, S., Mizuguchi, K., Yokota, H., Sasaki, T.*, Conformational plasticity of JRAB/MICAL-L2 provides “law and order” in collective cell migration, Molecular Biology of the Cell, 27(20), 3095-3108, 2016.
https://doi.org/10.1091/mbc.E16-05-0332
2015
Deguchi, S.*, Hotta, J., Yokoyama, S., Matsui, T.S., Viscoelastic and optical properties of four different PDMS polymers, Journal of Micromechanics and Microengineering, 25, 097002, 2015.
https://doi.org/10.1088/0960-1317/25/9/097002
Yokoyama, S., Kamei, Y., Matsui, T.S., Deguchi, S.*, Low-power laser processing-based approach to plasma lithography for cell micropatterning, Journal of Bioanalysis and Biomedicine, 7(3), 81–86, 2015.
https://doi.org/10.4172/1948-593X.1000128
Deguchi, S.*, Kudo, S., Matsui, T.S., Huang, W., Sato, M., Piezoelectric actuator-based cell microstretch device with real-time imaging capability, AIP Advances, 5(6), 067110, 2015.
https://doi.org/10.1063/1.4922220
2014
Yokoyama, S., Matsui, T.S., Deguchi, S.*, Microcontact peeling as a new method for cell micropatterning, PLOS ONE, 9(7), e102735, 2014.
https://doi.org/10.1371/journal.pone.0102735
Saito, A.C., Matsui, T.S., Ohishi, T., Sato, M., Deguchi, S.*, Contact guidance of smooth muscle cells is associated with tension-mediated adhesion maturation, Experimental Cell Research, 327(1), 1–11, 2014.
https://doi.org/10.1016/j.yexcr.2014.05.002
Deguchi, S.*, Nagasawa, Y., Saito, A.C., Matsui, T.S., Yokoyama, S., Sato, M., Development of motorized plasma lithography for cell patterning, Biotechnology Letters, 36(3), 507–513, 2014.
https://doi.org/10.1007/s10529-013-1391-3
Saito, A.C., Matsui, T.S., Sato, M., Deguchi, S.*, Aligning cells in arbitrary directions on a membrane sheet using locally formed microwrinkles, Biotechnology Letters, 36(2), 391-396, 2014.
https://doi.org/10.1007/s10529-013-1368-2
2013
Matsui, T.S., Sato, M., Deguchi, S.*, High extensibility of stress fibers revealed by in vitro micromanipulation with fluorescence imaging, Biochemical and Biophysical Research Communications, 434, 444-448, 2013.
https://doi.org/10.1016/j.bbrc.2013.03.093
Deguchi, S.*, Takahashi, S., Hiraki, H., Tanimura, S., Direct measurement of force exerted during single microbubble generation, Applied Physics Letters, 102, 084101, 2013.
https://doi.org/10.1063/1.4793532
2012
Deguchi, S.*, Matsui, T.S., Komatsu, D., Sato, M., Contraction of stress fibers extracted from smooth muscle cells: Effects of varying ionic strength, Journal of Biomechanical Science and Engineering, 7, 388-398, 2012.
https://doi.org/10.1299/jbse.7.388
Deguchi, S.*, Matsui, T.S., Sato, M., Simultaneous contraction and buckling of stress fibers in individual cells, Journal of Cellular Biochemistry, 113, 824-832, 2012.
https://doi.org/10.1002/jcb.23410
2011
Deguchi, S.*, Matsui, T.S., Iio, K., The position and size of individual focal adhesions are determined by intracellular stress-dependent positive regulation, Cytoskeleton, 68, 639-651, 2011.
https://doi.org/10.1002/cm.20541
Deguchi, S.*, Y Kawahara, S Takahashi, Cooperative regulation of vocal fold morphology and stress by the cricothyroid and thyroarytenoid muscles, Journal of Voice, 25, e255-e263, 2011.
https://doi.org/10.1016/j.jvoice.2010.11.006
Deguchi, S.*, Takahashi, S., Tanimura, S., Hiraki, H., Producing single microbubbles with controlled size using microfiber, Advances in Bioscience and Biotechnology, 2, 385-390, 2011.
https://doi.org/10.4236/abb.2011.25056
Deguchi, S.*, Bamba, H., Measuring surface geometry of adherent cells using oblique transillumination, Advances in Bioscience and Biotechnology, 2, 359-363, 2011.
https://doi.org/10.4236/abb.2011.25053
Deguchi, S.*, Kawahara, Y., Simulation of human phonation with vocal nodules, Am. J. Comp. Math., 1, 189-201, 2011.
https://doi.org/10.4236/ajcm.2011.13022
Matsui, T.S., Kaunas, R., Kanzaki, M., Sato, M., Deguchi, S.*, Non-muscle myosin II induces disassembly of actin stress fibres independently of myosin light chain dephosphorylation, Interface Focus, 1, 754-766, 2011. (Selected for the cover art of the issue)
https://doi.org/10.1098/rsfs.2011.0031
Kaunas, R.*, Deguchi, S., Multiple roles for myosin II in tensional homeostasis under mechanical loading, Cellular and Molecular Bioengineering, 4, 182-191, 2011.
https://doi.org/10.1007/s12195-011-0175-x
Deguchi, S.*, Mechanism of and threshold biomechanical conditions for falsetto voice onset, PLoS ONE 6, e17503, 2011.
https://doi.org/10.1371/journal.pone.0017503
Kaunas, R.*, Hsu, H., Deguchi, S., Sarcomeric model of stretch-induced stress fiber reorganization, Cell Health and Cytoskeleton, 3, 13-22, 2011.
https://doi.org/10.2147/CHC.S14984
2010
C. Lee, C. Haase, S. Deguchi, R. Kaunas*, Cyclic stretch-induced stress fiber dynamics – Dependence on strain rate, rho kinase and MLCK, Biochemical and Biophysical Research Communications, 401, 344-349, 2010.
https://doi.org/10.1016/j.bbrc.2010.09.046
Matsui, T.S., Ito, K., Kaunas, R., Sato, M., Deguchi, S.*, Actin stress fibers are at a tipping point between conventional shortening and rapid disassembly at physiological levels of MgATP, Biochemical and Biophysical Research Communications, 395, 301-306, 2010.
https://doi.org/10.1016/j.bbrc.2010.03.150
2009
Deguchi, S.*, Sato, M., Biomechanical properties of actin stress fibers of non-motile cells, Biorheology, 46, 93-105, 2009.
https://doi.org/10.3233/bir-2009-0528
Matsui, T.S.*, Deguchi, S., Sakamoto, N., Ohashi, T., Sato, M., A versatile micro-mechanical tester for actin stress fibers isolated from cells, Biorheology, 46, 401-415, 2009.
https://doi.org/10.3233/bir-2009-0551
Deguchi, S.*, Hyakutake, T., Theoretical consideration of the flow behavior in oscillating vocal fold, Journal of Biomechanics, 42, 824-829, 2009.
https://doi.org/10.1016/j.jbiomech.2009.01.027
Deguchi, S.*, Ishimaru,Y., Hashimoto, K., Washio, S., Tsujioka, K., Measurement and finite element modeling of the force balance in the vertical section of adhering vascular endothelial cells, Journal of the Mechanical Behavior of Biomedical Materials, 2, 173-185, 2009.
https://doi.org/10.1016/j.jmbbm.2008.07.003
2008
S Washio*, S Takahashi, K Murakami, T Tada, S Deguchi, Cavity generation by accelerated relative motions between solid walls contacting in liquid. Proc. IMechE, Part C, Journal of Mechanical Engineering Science, 222, 1695-1706, 2008.
https://doi.org/10.1243/09544062JMES965
S Washio*, S Takahashi, K Murakami, T Tada, S Deguchi, Cavity generation by accelerated relative motions between solid walls contacting in liquid. Trans Jpn Soc Mech Eng B, 74, 1376-1385, 2008.
https://doi.org/10.1299/kikaib.74.1376
S Deguchi* and K Kawashima, Computer-aided technique for automatic determination of the relationship between transglotatl pressure change and voice fundamental frequency. Annals of Otology, Rhinology & Laryngology, 117, 876-880, 2008.
https://doi.org/10.1177/000348940811701202
2007
S Deguchi*, Y Ishimaru, S Washio, Preliminary evaluation of stroboscopy system using multiple light sources for observation of pathological vocal fold oscillatory pattern, Annals of Otology, Rhinology & Laryngology, Vol 116, 9, 687-694, 2007.
https://doi.org/10.1177/000348940711600911
S. Deguchi*, M. Yano, K. Hashimoto, H. Fukamachi, S. Washio, K. Tsujioka, Assessment of the mechanical properties of the nucleus inside a spherical endothelial cell based on micro-tensile testing. Journal of Mechanics of Materials and Structures, Vol 2, No 6, 1087-1102, 2007.
https://doi.org/10.2140/jomms.2007.2.1087
S. Deguchi*, Y. Matsuzaki, T. Ikeda, Numerical analysis of effects of transglottal pressure change on fundamental frequency of phonation. Annals of Otology, Rhinology & Laryngology, Vol 116, No 2, 128-134, 2007.
https://doi.org/10.1177/000348940711600209
2006
T. Hyakutake*, S. Deguchi, A. Shiota, Y. Nishioka, S. Yanase, S. Washio, Effect of constriction oscillation on flow for potential application to vocal fold mechanics: numerical analysis and experiment. Journal of Biomechanical Science and Engineering, Vol. 1, No. 2, 290-303, 2006.
https://doi.org/10.1299/jbse.1.290
S. Deguchi*, Y. Miyake, Y. Tamura, S. Washio, Wavelike motion of a mechanical vocal fold model at the onset of self-excited oscillation. Journal of Biomechanical Science and Engineering, Vol 1, No 1, 246-255, 2006.
https://doi.org/10.1299/jbse.1.246
S. Deguchi*, T. Ohashi, M. Sato, Tensile properties of single stress fibers isolated from cultured vascular smooth muscle cells. Journal of Biomechanics, 39, 2603-2610, 2006.
https://doi.org/10.1016/j.jbiomech.2005.08.026
2005
Deguchi, S. *, Ishimaru, Y., Washio, S., Laryngo-stroboscopy for observation of pathological vocal fold oscillation, Transactions of the Japanese Society for Medical and Biological Engineering 43, 4, 709-716, 2005.
https://doi.org/10.11239/jsmbe.43.709
S. Deguchi*, T. Ohashi, M. Sato, Intracellular stress transmission through actin stress fiber network in adherent vascular cells. Mol Cell Biomech, Vol 2, No 4, 205-216, 2005.
https://doi.org/10.3970/mcb.2005.002.205
S. Deguchi*, T. Ohashi, M. Sato, Evaluation of tension in actin bundle of endothelial cells based on preexisting strain and tensile properties measurements. Mol Cell Biomech, Vol 2, No 3, 125-134, 2005.
https://doi.org/10.3970/mcb.2005.002.125
S. Deguchi*, T. Ohashi, M. Sato, Newly designed tensile test system for in vitro measurement of mechanical properties of cytoskeletal filaments. JSME International Journal Series C, Vol 48, No 4, 396-402, 2005.
[Awarded JSME Medal for Outstanding Paper by JSME]
https://doi.org/10.1299/jsmec.48.396
S. Deguchi*, K. Maeda, T. Ohashi, M. Sato, Flow-induced hardening of endothelial nuclei as an intracellular stress-bearing organelle. Journal of Biomechanics, 38, 1751-1759, 2005.
[F1000Prime recommended by Faculty of 1000]
https://doi.org/10.1016/j.jbiomech.2005.06.003
2002
Sato, M.*, Sakamoto, N., Deguchi, S., Katoh, M., and Abe, K., Vitamin E inhibits leukocyte adhesion and platelet aggregation, Jpn J Med Pharm Sci, 47, 457-461, 2002.
Reviews and book chapters
出口真次，李泓翰，松永大樹，松井翼，細胞発生力顕微鏡：画像から細胞の力学を予測する，生物物理，62(4), 2022.（表紙採用）
眞鍋康子，濱口裕貴，出口真次，松井翼，筋細胞を用いた筋機能の定量的評価 – 創薬や身体トレーニングの開発への応用，健康寿命の鍵を握る骨格筋 代謝・内分泌を介した全身性制御の分子基盤から運動による抗老化まで，Vo. 4, No. 2, 127 (263), 2022.
出口真次，研究ストーリー 生きている証，日本機械学会 Vol. 122, 2019.
出口 真次，松井 翼，市川 尚文，木岡 紀幸，細胞収縮力アッセイ, 月刊「細胞」, 51(3), 39-42, 2019.
出口 真次，松井 翼，市川 尚文，木岡 紀幸，細胞収縮力のアッセイ − メカノバイオロジー研究のツール，Precision Medicine プレシジョンメディシンと創薬，北隆館 ニューサイエンス社，2018．
出口真次，4.4 バイオテクノロジー・バイオインフォマティクス，機械工学年鑑2018
出口真次, 高度物理刺激と生体応答. 2.2.7節 細胞の力学応答における張力ホメオスタシスの役割. 養賢堂, 2017.
出口真次, 細胞のマルチスケールメカノバイオロジー. 第4章 細胞接着のメカノバイオロジー: 細胞収縮性に依存した機能調節の仕組み. 森北出版, 2017.
Kaunas, R., Deguchi, S., Cyclic stretch-induced reorganization of stress fibers in endothelial cells. In Vascular Engineering. Eds: Tanishita, K., Yamamoto, K., Springer, 99-110, 2016.
出口真次, 松井翼, 佐藤正明, Dojin Bioscienceシリーズ・メカノバイオロジー. 細胞が力を感じ応答する仕組み. 第2章 細胞における力の発生と維持機構. 17-33, 2015.
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