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日時：2025年7月17日(木) 10:30-11:30
場所：Grad Sch Eng Sci, Building D, 4th floor, seminar room (基礎工4階D棟セミナー室)
講演者：Yun Jung Heo (ホ・ユンジョン先生), Ph.D.
Professor, Kyung Hee University (慶熙大学), 韓国
タイトル：Fluorescent sensors for continuous glucose monitoring
要旨：
Diabetes affects approximately 14% of the global adult population, leading to a range of complications and even death. To manage diabetes more effectively, non-invasive continuous glucose monitoring (CGM) is gaining attention over traditional intermittent, blood-based methods. In this presentation, we introduce boronic acid-based fluorescent sensors for continuous glucose monitoring. The fluorescent sensors enable non-enzymatic, reversible glucose detection and are suitable for long-term use in the body. Using this approach, we developed hydrogel microsensors [1,2], microneedles [3], and nanoparticles, and demonstrated their performance for continuous monitoring. Boronic acid-based fluorescent sensors hold great promise for metabolic research and clinical applications.
References
[1] Shibata, H., Heo, Y. J. et al., (2010) PNAS, 107(42), 17894-17898.
[2] Heo, Y. J. et al., (2011) PNAS, 108(33), 13399-13403.
[3] Jung Y., Heo Y. J., Yu, K. J. et al., (2023) Sci. Adv., 9(22), eadh1765.